A lyse kit, also known as a lysis kit, is a package or set of substances used to break open or lyse cells in biological samples. The purpose of a lyse kit is to release the intracellular contents, such as proteins, nucleic acids, or organelles, for further analysis or processing.

Lyse kits are commonly used in molecular biology, biochemistry, and diagnostic laboratories when working with cell-based samples, such as blood, tissues, or cultured cells.